Tag Archives: antibacterial

Promox® (105mL)

Antibiotics, , , , ,

Promox® (105mL)

INDICATIONS:

For the treatment of infections caused by susceptible strains of Gram-positive and Gram-negative organisms such as respiratory, G.I. and genito-urinary tracts, skin and soft tissue infections.

DESCRIPTION:

Amoxicillin is a semi-synthetic penicillin a close chemical and a pharmacological relative of ampicillin. The drug is stable in acid and is designed for oral use. The antimicrobial spectrum of amoxicillin is essentially identical to that of ampicillin with the important exception that amoxicillin appears to be less effective than ampicillin for shigellosis. Amoxicillin is more rapidly and completely absorbed from the gastrointestinal tract than ampicillin, which is the major difference between the two. Peak concentration in plasma are two to two and one-half times greater for amoxicillin than for ampicillin after oral administration of the same dose. Food does not interfere with absorption, perhaps because of more complete absorption of this congener.

FORMULATION:

Each 5 mL (1 teaspoonful) contains:
Amoxicillin (as trihydrate) …………………….. 250 mg

PRECAUTION:

Amoxicillin is contraindicated in patients known to be sensitive to penicillin and it should be used with caution in patients with known history of allergy to the drug.

UNDESIRABLE EFFECTS:

Gastrointestinal disturbances and rashes may occur. Small accounts of amoxicillin excreted in the milk may provoke allergic reactions in breastfeed infants.

DOSAGE:

CAPSULE:
Adult Dose: One capsule every 6 hours or as prescribed by the physician.
SUSPENSION:
1-2 years: 2.5 mL (1/2 teaspoon)
3-6 years: 5 mL (1 teaspoonful)
7-12 years: 5-10 mL (1-2 teaspoonfuls) every 8 hours or as prescribed by the physician.

DIRECTION FOR RECONSTITUTION:

For 250 mg/5 mL Powder for Suspension
To make 60 mL reconstituted suspension, mix thoroughly the contents with 45 mL water and shake well until the powder is evenly suspended. The reconstituted suspension is stable for 7 days at temperatures not exceeding 30 degree Celsius and 14 days when refrigerated (2 degree Celsius – 8 degree Celsius).

CAUTION:

Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

STORAGE CONDITION:

Store at temperatures not exceeding 30 degree Celsius.

AVAILABILITY:

Amber bottle x 105 mL
Amber bottle x 60 mL
Amber bottle x 30 mL

Procor® (75mL)

Antibiotics, , , ,

Procor® (75mL)

MECHANISM OF ACTION:

The antimicrobial activity of the combination of trimethoprim and sulfamethoxazole resultsfrom its actions or two steps of the enzymatic pathway for the synthesis of tetrahydrofolic acid. Sulfonamide inhibits the incorporation of PABA into folic acid and trimethoprim prevents the reduction of dehydrofolate to tetrahydrofolate. The latter is the form of folate essential for one carbon trasfer reactions. The synergistic interaction between the sulfonamide and trimethoprim is this predictable from their respective mechanism.

INDICATIONS:

Urinary tract infections, respiratory tract infections, gastro-intestinal tract infections, and other infections suspectible to its components.

FORMULATION:

Each 5 mL (1 teaspoonful) contains:
Sulfamethoxazole ……………………… 200 mg
Trimethoprim …………………………. 40 mg

DOSAGE:

Suspension:
6-12 years: 10 mL (2 teaspoonful)
2-6 years: 5 mL (1 teaspoonful)
Below 2 years: 2.5 mL (1/2 teaspoon). Twice a day or as prescribed by the physician.

PRECAUTION:

In cases with renal impairment, a reduced or more widely spaced dosage is indicated to avoid accumulation in the blood. For such patient measurement of plasma concentration are advisable. Regular blood count are recommended whenever Cotrimoxazole is given to a long period. Nausea, vomiting, glossitis and skin rashes have occasionally been reported and high doses may cause diarrhea in small number of patients treated with Cotrimoxazole.

CAUTION:

Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

AVAILABILITY:

Strip Foil of 10’s; box of 100’s
Blister Pack of 10’s box of 20’s and 100’s
Bottle x 60 mL & 75 mL

STORAGE CONDITION:

Store at temperatures not exceeding 30 degree Celsius.

SHAKE WELL BEFORE USING.

 

Promox® (500mg)

Antibiotics, , , ,

Promox® (500mg)

DESCRIPTION:

Amoxicillin is a semi-synthetic penicillin a close chemical and a pharmacological relative of ampicillin. The drug is stable in acid and is designed for oral use. The antimicrobial spectrum of amoxicillin is essentially identical to that of ampicillin with the important exception that amoxicillin appears to be less effective than ampicillin for shigellosis. Amoxicillin is more rapidly and completely absorbed from the gastrointestinal tract than ampicillin, which is the major difference between the two. Peak concentration in plasma are two to two and one-half times greater for amoxicillin than for ampicillin after oral administration of the same dose. Food does not interfere with absorption, perhaps because of more complete absorption of this congener.

FORMULATION:

Each capsule contains:
Amoxicillin (as trihydrate) …………………….. 500 mg

INDICATIONS:

For the treatment of infections caused by susceptible strains of Gram-positive and Gram-negative organisms such as respiratory, G.I. and genito-urinary tracts, skin and soft tissue infections.

PRECAUTION:

Amoxicillin is contraindicated in patients known to be sensitive to penicillin and it should be used with caution in patients with known history of allergy to the drug.

UNDESIRABLE EFFECTS:

Gastrointestinal disturbances and rashes may occur. Small accounts of amoxicillin excreted in the milk may provoke allergic reactions in breastfeed infants.

DOSAGE:

CAPSULE:
Adult Dose: One capsule every 6 hours or as prescribed by the physician.
SUSPENSION:
1-2 years: 2.5 mL (1/2 teaspoon)
3-6 years: 5 mL (1 teaspoonful)
7-12 years: 5-10 mL (1-2 teaspoonfuls) every 8 hours or as prescribed by the physician.

DIRECTION FOR RECONSTITUTION:

For 250 mg/5 mL Powder for Suspension
To make 60 mL reconstituted suspension, mix thoroughly the contents with 45 mL water and shake well until the powder is evenly suspended. The reconstituted suspension is stable for 7 days at temperatures not exceeding 30 degree Celsius and 14 days when refrigerated (2 degree Celsius – 8 degree Celsius).

CAUTION:

Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

STORAGE CONDITION:

Store at temperatures not exceeding 30 degree Celsius.

AVAILABILITY:

In blister pack x 100’s