Tag Archives: 500mg

Dostan®

Miscellaneous, , ,

Dostan® (500 mg)

DESCRIPTION:

Tranexamic Acid is an antifibrinolytic agent used mainly in the treatment and prophylaxis of haemorrhage associated with excessive fibrinolysis. It is given by mouth, by slow intravenous injection, or limited to gastro-intestinal disturbances, hypotension has occured, particularly afer rapid intravenous infusion.

ADVERSE EFFECTS:

Tranexamic Acid appears to be well tolerated.It can produce dose-related gastro-intestinal disturbances. Hyportension has occured, particularly after rapid intravenous administration. Thrombotic complications have been reported in patients receiving Tranexamic Acid, but these are usually a consequence of its inappropriate use.

PRECAUTION:

Should not be used in patients with active intravascular clotting because of the risk of thrombosis. Patients with a predisposition to thrombosis are also at rish it given antibrinolytic therapy. Haemorrhage due to disseminated intravascular coaguflation should therefore not be treated not be treated with antifibrinclytic compounds unless the condition is predominantly due to disturbances in fibrinolytic mechanisms; Tranexamic Acid has been used when the latter conditions are met, but with careful monitoring and anticoagulant cover.

PHARMACOKINETICS:

Tranexamic Acid is rapidly absorbed from the gastrointestinal tract, absorption is 30 to 50%. It is widely distributed throughout the body, diffuses acroos the placenta, and has been detected in breast milk. It has a plasma elimination half-life of about 2 hours. It is excreted in the urine mainly as unchanged drug.

INDICATIONS:

It is used in the treatment and prophylaxis of haemorrhage associated with excessive librinolysis. It is also used in the prophylaxis of hereditary angloedema.

DOSAGE:

Usual adult dose: 1 to 1.5 g (for 15 to 25 mg per kg body weight). 2 to 4 times daily, or as prescribed by the physician.

CAUTION:

Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

AVAILABILITY:

Blister Pack x 10’s (Box of 100’s)

STORAGE CONDITION:

Store at temperatures not exceeding 30 degree Celsius.

Korn C®

Vitamin c, , , , , ,

Korn C®

DESCRIPTION:

KORN C is a 500 mg Chewable Capsule vitamin

FORMULATION:

Each 500 mg capsule contains:

Ascorbic acid ……………………………….125 mg
Ascorbic acid (as Sodium ascorbate) …..375 mg

INDICATIONS:

For the treatment and prevention of Vitamin C deficiency.

PRECAUTION:

Ascorbic Acid should be given with care to patients with hyperoxaluria. Tolerance may be included in patients taking high doses.

DOSAGE:

One tablet daily or as prescribed by the physician.

ADVERSE EFFECTS:

Large doses are reported to cause diarrhea and other gastrointestinal disturbances and are associated with the formation of renal calcium oxalate calculi.

CAUTION:

Food, Drugs, Devices and Cosmetics Acts prohibits dispensing without prescription.

STORAGE CONDITION:

Store at temperatures not exceeding 30 degree Celsius.

AVAILABILITY:

Blister Pack x 10’s (Box of 100’s)

Promox® (500mg)

Antibiotics, , , ,

Promox® (500mg)

DESCRIPTION:

Amoxicillin is a semi-synthetic penicillin a close chemical and a pharmacological relative of ampicillin. The drug is stable in acid and is designed for oral use. The antimicrobial spectrum of amoxicillin is essentially identical to that of ampicillin with the important exception that amoxicillin appears to be less effective than ampicillin for shigellosis. Amoxicillin is more rapidly and completely absorbed from the gastrointestinal tract than ampicillin, which is the major difference between the two. Peak concentration in plasma are two to two and one-half times greater for amoxicillin than for ampicillin after oral administration of the same dose. Food does not interfere with absorption, perhaps because of more complete absorption of this congener.

FORMULATION:

Each capsule contains:
Amoxicillin (as trihydrate) …………………….. 500 mg

INDICATIONS:

For the treatment of infections caused by susceptible strains of Gram-positive and Gram-negative organisms such as respiratory, G.I. and genito-urinary tracts, skin and soft tissue infections.

PRECAUTION:

Amoxicillin is contraindicated in patients known to be sensitive to penicillin and it should be used with caution in patients with known history of allergy to the drug.

UNDESIRABLE EFFECTS:

Gastrointestinal disturbances and rashes may occur. Small accounts of amoxicillin excreted in the milk may provoke allergic reactions in breastfeed infants.

DOSAGE:

CAPSULE:
Adult Dose: One capsule every 6 hours or as prescribed by the physician.
SUSPENSION:
1-2 years: 2.5 mL (1/2 teaspoon)
3-6 years: 5 mL (1 teaspoonful)
7-12 years: 5-10 mL (1-2 teaspoonfuls) every 8 hours or as prescribed by the physician.

DIRECTION FOR RECONSTITUTION:

For 250 mg/5 mL Powder for Suspension
To make 60 mL reconstituted suspension, mix thoroughly the contents with 45 mL water and shake well until the powder is evenly suspended. The reconstituted suspension is stable for 7 days at temperatures not exceeding 30 degree Celsius and 14 days when refrigerated (2 degree Celsius – 8 degree Celsius).

CAUTION:

Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

STORAGE CONDITION:

Store at temperatures not exceeding 30 degree Celsius.

AVAILABILITY:

In blister pack x 100’s