Category Archives: Miscellaneous

Periodent

Miscellaneous, ,

Periodent Dental Gel

INDICATION:

Gingivitis, teething pain, irritation, cold sores & aphthous-ulceration. Oral candidal or bacterial infections also. It is indicated to reduce dental plague accumulation. It is indicated for patients having coexisting gingivitis and periodontis.

FORMULATION:

Metronidazole 1.0% w/w
(As Metronidazole Benzoate)
Chlorhexidine Gluconate Solution 0.25% w/w
Lidocaine Hydrochloride 2.0 w/w
(equivalent to Anhydrous Lidocaine Hydrochloride)
Water Soluble Gel Base q.s.

PHARMACEUTICAL DOSAGE FORM:

Dental Gel

PRECAUTIONS:

“Carefully read the instructions before use. Consult your doctor for further information.”
“Use upon doctor’s prescription only”

NECESSARY INFORMATION BEFORE USE:
Contraindications:

It should not be used in any patient who has a known sensitivity to Chlorhexidine, Metronidazole and Lidocaine Hydrochloride or any of the ingredients of the product.

Precautions:

For patients having coexisting gingivitis and periodontitis, the presence or absence of gingival inflamation following treatment with PERIODENT Dental gel should not be used as major indicator of underlying periodontis.

PERIODENT Dental gel can cause staining of oral surfaces, such as tooth surfaces, restorations, and the dorsum of the tongue. Stain will be more pronounced in patients who have heavier accumulations of un-removed plaque. Stain can be removed from most tooth surfaces by a conventional professional prophylactic technique. If natural stain can not be removed form these surfaces be dental prophylaxis, patients should be excluded from PERIODENT Dental gel treatment if permanent discoloration is unacceptable.

Patients information

For oropharyngal use only. Avoid contact with eye.
Patients should be instructed to strictly adhere to dosage instructions and to keep the medication out of the reachof children.

Drug Interactions

No reports of drug interaction were located.

ADHERE EFFECTS:

The most common side effects are an increase staining of teeth and other oral surfaces, an increase in calculus formation adn an alteration in taste perception. No serious systemic adverse reactions associated with use of PERIODENT dental gel were observed i clinical testing. Minor irritation and superficial desquamation of the oral mucosa have been noted in patients using PERIODENT dental gel, particularly among children. “Inform your doctor in case of any adverse reactions related to drug use”

INSTRUCTIONS FOR USE:
Dosage ad Administration

Adult: Apply enough gel to cover the finger tip and rub gently onto the effected area, not more often than 3 hourly.

Children: Not recommended for children below 4 months.

SHELF LIFE:

24 months from the date of manufacturing

STORAGE:

Storage at the temperature not exceeding 30 degree celcius.
Protect from light. Keep out of the reach of children.

PRESENTATION:

10 gram gel in an Aluminum collapsible tube.
20 gram gel in an Aluminum collapsible tube.
Each tube is packed in an unit carton with package insert.

Prox-S®

Miscellaneous, , , ,

Prox-S® (120 mL)

ACTIONS AND USES:

Salbutamol is a directly acting sympathomimetic amine with actions similar to those described under isoprenaline Sulfate. Its main action, however, is on the adrenergic receptors in the bronchi and the respiratory tract rather than on the cardiac receptors. For this reason, it induces bronchodilation and inhibits brochospasm in doses which do not produce marked cardiac acceleration. It is used in the treatment of asthma, chronic bronchitis, emphysema, and other bronchopulmonary disorders involving bronchospasm.

ADVERSE EFFECTS:

Palpitation and tachycardia may occur in some patients.

PRECAUTIONS AND CONTRAINDICATIONS:

It is contraindicated in patients with hypertension, myocardial insufficiency, and hyperthyroidism. The excessive use of sprays containing salbutamol should be avoided as it may lead to fatal results. Salbutamol should not be administered with non-selective beta-adrenoreceptor blocking drugs such as propranolol or exprenolol.

DOSAGE:

Children:
13 years and above: 5-10 mL (1-2 teaspoonfuls)
7-12 years: 5 mL (1 teaspoonful)
2-6 years: 2.5 mL (1/2 teaspoon)
To be taken three times a day, or as prescribed by the physician.

CAUTION:

Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

AVAILABILITY:

Bottle x 60 mL
Bottle x 120 mL

STORAGE:

Store at temperatures not exceeding 30 degree Celsius.

Dostan®

Miscellaneous, , ,

Dostan® (500 mg)

DESCRIPTION:

Tranexamic Acid is an antifibrinolytic agent used mainly in the treatment and prophylaxis of haemorrhage associated with excessive fibrinolysis. It is given by mouth, by slow intravenous injection, or limited to gastro-intestinal disturbances, hypotension has occured, particularly afer rapid intravenous infusion.

ADVERSE EFFECTS:

Tranexamic Acid appears to be well tolerated.It can produce dose-related gastro-intestinal disturbances. Hyportension has occured, particularly after rapid intravenous administration. Thrombotic complications have been reported in patients receiving Tranexamic Acid, but these are usually a consequence of its inappropriate use.

PRECAUTION:

Should not be used in patients with active intravascular clotting because of the risk of thrombosis. Patients with a predisposition to thrombosis are also at rish it given antibrinolytic therapy. Haemorrhage due to disseminated intravascular coaguflation should therefore not be treated not be treated with antifibrinclytic compounds unless the condition is predominantly due to disturbances in fibrinolytic mechanisms; Tranexamic Acid has been used when the latter conditions are met, but with careful monitoring and anticoagulant cover.

PHARMACOKINETICS:

Tranexamic Acid is rapidly absorbed from the gastrointestinal tract, absorption is 30 to 50%. It is widely distributed throughout the body, diffuses acroos the placenta, and has been detected in breast milk. It has a plasma elimination half-life of about 2 hours. It is excreted in the urine mainly as unchanged drug.

INDICATIONS:

It is used in the treatment and prophylaxis of haemorrhage associated with excessive librinolysis. It is also used in the prophylaxis of hereditary angloedema.

DOSAGE:

Usual adult dose: 1 to 1.5 g (for 15 to 25 mg per kg body weight). 2 to 4 times daily, or as prescribed by the physician.

CAUTION:

Foods, Drugs, Devices and Cosmetics Act prohibits dispensing without prescription.

AVAILABILITY:

Blister Pack x 10’s (Box of 100’s)

STORAGE CONDITION:

Store at temperatures not exceeding 30 degree Celsius.